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Ultevursen

Ultevursen

Item no.	HY-147412-1ea
Manufacturer	MedChem Express
CASRN	2642382-41-8
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]International Nonproprietary Names for Pharmaceutical Substances (INN). WHO Drug Information, Vol. 36, No. 2, 2022.
Smiles	[Ultevursen]
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	QR-421a
Shipping Condition	Room temperature
Available
Manufacturer - Type	Oligonucleotides
Manufacturer - Targets	Nucleoside Antimetabolite/Analog
Shipping Temperature	Room temperature
Molecular Weight	8372.24
Product Description	Ultevursen (QR-421a) is a single-stranded RNA based oligonucleotide that is designed to skip exon 13 in the RNA with the aim to stop vision loss in people that have retinitis pigmentosa due to a mutation in exon 13 of the USH2A gene (encoding usherin). Ultevursen sequence: (P-thio)[2′-O-(2-methoxyethyl)](A-G-m5C-m5U-m5U-m5C-G-G-A-G-A-A-A-m5U-m5U-m5U-A-A-A-m5U-m5C)[1].
Manufacturer - Research Area	Others
Solubility	10 mM in DMSO
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	Phase 3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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