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Alpha-Estradiol-d2

Alpha-Estradiol-d2

Item no.	HY-B0141AS1-5mg
Manufacturer	MedChem Express
CASRN	81586-94-9
Amount	5 mg
Quantity options	1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.0
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.\|[2]Santos RS, et al. The effects of 17 alpha-estradiol to inhibit inflammation in vitro. Biol Sex Differ. 2017 Sep 6;8:30.\|[3]Schriefers H, et al. Inhibition of testosterone metabolism by 17-alpha-estradiol in rat liver slices. Arzneimittelforschung. 1991 Nov;41(11):1186-9.\|[4]Zhang HB, et al. 17-Alpha-estradiol ameliorating oxygen-induced retinopathy in a murine model. Jpn J Ophthalmol. 2012 Jul;56(4):407-15.
Smiles	C[C@@]12[C@H](O)CC[C@@]1([H])[C@]3([H])CCC4=C(C=C([2H])C(O)=C4[2H])[C@@]3([H])CC2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Alfatradiol-d2,Epiestradiol-d2,Epiestrol-d2
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	Metabolism-sugar/lipid metabolism
Manufacturer - Targets	5 alpha Reductase; Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	274.39
Product Description	Alpha-Estradiol-d2 is the deuterium labeled Alpha-Estradiol. Alpha-Estradiol is a weak estrogen and a 5α-reductase inhibitor which is used as a topical medication in the treatment of androgenic alopecia[1].
Manufacturer - Research Area	Metabolic Disease; Cardiovascular Disease
Solubility	10 mM in DMSO\|DMSO: 62.5mg/mL (ultrasonic; warming; heat to 60°C)\|Ethanol: 11.11mg/mL (ultrasonic)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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HY-B0141AS1-5mg-safety-datasheet.pdf