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Isovaleramide

Isovaleramide

Item no.	HY-B1229-50mg
Manufacturer	MedChem Express
CASRN	541-46-8
Amount	50 mg
Quantity options	100 mg 10 mM/1 mL 25 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.0
Citations	[1]Giraldo SE, et al. Isovaleramida, principio anticonvulsivo aislado de Valeriana pavonii [Isovaleramide, an anticonvulsant molecule isolated from Valeriana pavonii]. Biomedica. 2010 Apr-Jun;30(2):245-50.\|[2]Yang K, et al. Isovaleramide attenuates ethylene glycol poisoning‐induced acute kidney injury and reduces mortality by inhibiting alcohol dehydrogenase activity in rats[J]. Basic & Clinical Pharmacology & Toxicology, 2024.\|[3]Park H J, et al. Studies on the components of valerian and isovaleramide[J]. YAKHAK HOEJI, 2010, 54(1): 1-7.\|[4]Manavi M A. Exploring Valeriana species: Unraveling anticonvulsant potential through phytochemistry and pharmacology. Future Natural Products, 2024, 9(2): 100-110.
Smiles	CC(C)CC(N)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	3-Methylbutanamide
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	GABA Receptor
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	101.15
Product Description	Isovaleramide (3-Methylbutanamide) is an orally active anticonvulsant. Isovaleramide inhibits alcohol dehydrogenase (ADH) activity and regulates GABAergic system. Isovaleramide reduces acute kidney injury. Isovaleramide has antiepileptic, anxiolytic, sedative and hypnotic effects[1][2][3][4].
Manufacturer - Research Area	Metabolic Disease; Neurological Disease
Solubility	DMSO: 250 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Clinical information	Phase 2

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HY-B1229-50mg-safety-datasheet.pdf