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1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one

1,7-Bis(4-hydroxyphenyl)-hepta-4E,6E-dien-3-one

Item no.	HY-N0998-1ea
Manufacturer	MedChem Express
CASRN	332371-82-1
Amount	1 ea
Quantity options	100 mg 1 ea 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Ali MS, et al. Six new diarylheptanoids from the seeds of Alpinia blepharocalyx. J Nat Prod. 2001 Mar;64(3):289-93.\|[2]Matsumoto T, et al. Diarylheptanoids with inhibitory effects on melanogenesis from the rhizomes of Curcuma comosa in B16 melanoma cells. Bioorg Med Chem Lett. 2013 Sep 15;23(18):5178-81.
Smiles	O=C(/C=C/C=C/C1=CC=C(O)C=C1)CCC2=CC=C(O)C=C2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	Melanocortin Receptor
Shipping Temperature	Room temperature
Molecular Weight	294.34
Product Description	1, 7-Bis(4-hydroxyphenyl)-hepta-4E, 6E-dien-3-one (compound 6) shows antiproliferative activity with ED50s of 57.7, 78.8 μM for 26-L5 and HT-1080 cells, respectively. 1, 7-Bis(4-hydroxyphenyl)-hepta-4E, 6E-dien-3-one inhibits melanogenesis in B16 melanoma 4A5 cells. 1, 7-Bis(4-hydroxyphenyl)-hepta-4E, 6E-dien-3-one has the potential for the research of skin disorders[1][2].
Manufacturer - Research Area	Cancer
Solubility	10 mM in DMSO
Manufacturer - Pathway	GPCR/G Protein; Neuronal Signaling
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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