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2,3-Dihydro-3α-methoxynimbolide

2,3-Dihydro-3α-methoxynimbolide

Item no.	HY-N10091-1ea
Manufacturer	MedChem Express
CASRN	1607828-35-2
Amount	1 ea
Quantity options	100 mg 1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1] Manosroi A, et al. Limonoids from Azadirachta indica var. siamensis extracts and their cytotoxic and melanogenesis-inhibitory activities. Chem Biodivers. 2014;11(4):505-531.
Smiles	C[C@@]12[C@@](O[C@@]3([H])C2=C([C@@](C4=COC=C4)([H])C3)C)([H])[C@@]5([H])[C@]6([H])[C@@]([C@H]1CC(OC)=O)(C(C[C@H]([C@]6(C(O5)=O)C)OC)=O)C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Targets	Apoptosis
Shipping Temperature	Room temperature
Molecular Weight	498.56
Product Description	2, 3-Dihydro-3α-methoxynimbolide is a limonoid compound isolated from the extracts of bark, leaves, roots, and seeds of Azadirachta indica A. Juss. var. siamensis Valeton. 2, 3-Dihydro-3α-methoxynimbolide exhibits potent cyto-toxicities against one or more cell lines. 2, 3-Dihydro-3α-methoxynimbolide activates caspases-3, -8, and -9, while increases the ratio of Bax/Bcl-2. 2, 3-Dihydro-3α-methoxynimbolide induces apoptosis via both mitochondrial and death receptor pathways in AZ521[1].
Manufacturer - Research Area	Others
Solubility	10 mM in DMSO
Manufacturer - Pathway	Apoptosis
Clinical information	No Development Reported

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