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Semotiadil (recemate fumarate)

Semotiadil (recemate fumarate)

Item no.	HY-U00026-1ea
Manufacturer	MedChem Express
CASRN	123388-25-0
Amount	1 ea
Quantity options	100 mg 10 mg 1 ea 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Citations	[1]Koidl B, et al. A novel benzothiazine Ca<sup>2+</sup> channel antagonist, Semotiadil, inhibits cardiac L-type Ca<sup>2+</sup> currents. Eur J Pharmacol. 1997 Mar 19;322(2-3):243-7. [2]Teramoto N. Mechanisms of the inhibitory action of Semotiadil fumarate, a novel Ca antagonist, on the voltage-dependent Ca current in smooth muscle cells of the rabbit portal vein. Jpn J Pharmacol. 1993 Mar;61(3):183-95. [3]Ichikawa M, et al. Antihypertensive effects of a novel calcium antagonist, Semotiadil fumarate (SD-3211), alone and in combination with Enalapril or trichlormethiazide in spontaneously hypertensive rats. Biol Pharm Bull. 1994 Nov;17(11):1513-5.
Smiles	O=C(O)/C=C/C(O)=O.O=C1C(C2=CC(OC)=CC=C2OCCCN(CCOC3=CC=C(OCO4)C4=C3)C)SC5=CC=CC=C5N1C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	Calcium Channel
Shipping Temperature	Room temperature
Molecular Weight	652.71
Product Description	Semotiadil recemate fumarate is the recemate of Semotiadil fumarate. Semotiadil fumarate is a novel vasoselective Ca2+ channel antagonist.
Manufacturer - Research Area	Cardiovascular Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Clinical information	No Development Reported

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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