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5a-Pregnane-3,20-dione-d6

5a-Pregnane-3,20-dione-d6

Item no.	HY-W006492S-5mg
Manufacturer	MedChem Express
CASRN	203850-92-4
Amount	5 mg
Quantity options	10 mg 1 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.0
Citations	[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. \|[2]Wiebe JP, et al. The endogenous progesterone metabolite, 5a-pregnane-3,20-dione, decreases cell-substrate attachment, adhesion plaques, vinculin expression, and polymerized F-actin in MCF-7 breast cancer cells. Endocrine. 2001 Oct;16(1):7-14.
Smiles	C[C@@]12[C@]3([H])[C@](C([2H])C([2H])[C@@]1([2H])C([2H])C(C([2H])C2[2H])=O)([H])[C@@]4([H])[C@](CC3)([C@H](CC4)C(C)=O)C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Room temperature
Available
Manufacturer - Type	Isotope-Labeled Compounds
Manufacturer - Applications	Metabolism-protein/nucleotide metabolism
Manufacturer - Targets	Endogenous Metabolite
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	322.51
Product Description	5a-Pregnane-3, 20-dione-d6 is the deuterium labeled 5a-Pregnane-3, 20-dione. 5a-Pregnane-3, 20-dione is the endogenous progesterone metabolite.
Manufacturer - Research Area	Endocrinology; Cancer
Solubility	10 mM in DMSO\|DMSO: 6.67mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-W006492S-5mg-safety-datasheet.pdf