« Back
Home /
A 1070722

A 1070722

Item no.	TMO-T10202-2mg
Manufacturer	TargetMol
CASRN	1384424-80-9
Amount	2 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C17H13F3N4O2
Smiles	COc1ccc2c(NC(=O)Nc3cccc(n3)C(F)(F)F)ccnc2c1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	GSK-3,GSK-3
Shipping Condition	Cool pack
Available
Manufacturer - Targets	GSK-3
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	362.31
Description	A 1070722 is a potent and selective GSK-3 inhibitor, exhibiting high affinity for both GSK-3α (Ki = 0.6 nM) and GSK-3β (Ki = 0.6 nM). It can penetrate the blood-brain barrier (BBB) and accumulate in brain regions, indicating potential use as a PET radiotracer for quantifying GSK-3 in the brain.
Pathways	PI3K/Akt/mTOR signaling\|\|\|Stem Cells
Bioactivity	A 1070722 is a potent and selective GSK-3 inhibitor, with a Ki of 0.6 nM for both GSK-3Î± and GSK-3Î². It can penetrate the blood-brain barrier (BBB) and accumulates in brain regions, thus potential for PET radiotracer for the quantification of GSK-3 in bra

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T10202-2mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 2 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question