EC359

Item no.	TMO-T11146-200mg
Manufacturer	TargetMol
CASRN	2012591-09-0
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C36H38F2O2
Smiles	[H][C@@]12CC[C@@](O)(C(F)(F)C#C)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)-c1c(C)cc(C)cc1C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	EC-359
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	540.68
Description	EC359 is a potent and selective inhibitor of leukemia inhibitory factor receptor (LIFR), a potent inhibitor with anticancer activity, blocks LIF/LIFR interaction, and can be used in the study of leukemia and endometrial cancer.
Pathways	Apoptosis
Bioactivity	EC359Kd, 10.2 nM, interacts directly with LIFR and effectively blocks LIF/LIFR interaction. It is a potent, selective, highly affinity, and oral active leukemia inhibitor of LIFR.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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