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KY-05009

KY-05009

Item no.	TMO-T11793-50mg
Manufacturer	TargetMol
CASRN	1228280-29-2
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	Cc1ccc(cc1)C(=O)Nc1sc(Nc2ccccc2)nc1C(N)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Wnt/beta-catenin,Wnt/beta-catenin
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Wnt/beta-catenin
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	352.41
Description	KY-05009 is a chemical compound that effectively suppresses TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.
Pathways	Cytoskeletal Signaling\|\|\|Stem Cells

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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