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RIPK1-IN-7

RIPK1-IN-7

Item no.	TMO-T12731-200mg
Manufacturer	TargetMol
CASRN	2300982-44-7
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C25H22F3N5O2
Smiles	CCn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cccc(OC(F)(F)F)c2)c2c(N)ncnc12
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	RIP kinase,RIP kinase
Shipping Condition	Cool pack
Available
Manufacturer - Targets	RIP kinase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	481.47
Description	RIPK1-IN-7 is a potent and selective inhibitor of RIPK1 (Kd of 4 nM and enzymatic IC50 of 11 nM), exhibiting excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.
Pathways	Apoptosis\|\|\|NF-κB
Bioactivity	RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM), andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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