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CCR2 antagonist 4

CCR2 antagonist 4

Item no.	TMO-T13114-200mg
Manufacturer	TargetMol
CASRN	226226-39-7
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C21H21ClF3N3O2
Smiles	FC(F)(F)c1cccc(c1)C(=O)NCC(=O)N[C@@H]1CCN(Cc2ccc(Cl)cc2)C1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Teijin compound 1
Shipping Condition	Cool pack
Available
Manufacturer - Targets	CCR
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	439.86
Description	CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist with IC50 values of 180 nM and 24 nM for CCR2 inhibition and MCP-1-induced chemotaxis inhibition, respectively.
Pathways	Immunology/Inflammation\|\|\|GPCR/G Protein\|\|\|Microbiology/Virology
Bioactivity	CCR2 antagonist 4 is a potent and specific antagonist of CCR2(IC50s of 180 nM), and potently inhibits MCP-1-induced chemotaxis(IC50 of 24 nM).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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