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THS-044

THS-044

Item no.	TMO-T13925-200mg
Manufacturer	TargetMol
CASRN	62054-67-5
Amount	200 mg
Quantity options	100 mg 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C11H12F3N3O3
Smiles	[O-][N+](=O)c1cc(ccc1NN1CCOCC1)C(F)(F)F
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine, N-Morpholino-2-nitro-4-(trifluoromethyl)aniline
Shipping condition	Cool pack
Available
Manufacturer - Targets	HIF
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	291, 23
Description	THS-044 (N-[2-Nitro-4-(Trifluoromethyl)phenyl]morpholin-4-Amine) binding stabilizes the HIF2α PAS-B folded state with a kd of 2 μM and regulates HIF2 activity in endogenous and clinical settings.
Bioactivity	THS-044 binding stabilizes the HIF2Î± PAS-B folded state, for regulating HIF2 activity in endogenous and clinical settings.
Pathways	Chromatin/Epigenetic\|\|\|Angiogenesis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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