B022

Item no.	TMO-T14491-200mg
Manufacturer	TargetMol
CASRN	1202764-53-1
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C19H16ClN5OS
Smiles	CC(O)(C#Cc1ccc2CCN(c2c1)c1nc(N)ncc1Cl)c1nccs1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	NF-κB
Shipping Condition	Cool pack
Available
Manufacturer - Targets	NF-κB
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	397.88
Description	B022 is a selective and potent NF-κB-induced kinase (NIK) inhibitor (Ki: 4.2 nM) and a chemical probe for treating liver inflammation and injury, protecting the liver from inflammation and injury caused by oxidative stress and toxins.
Pathways	NF-κB
Bioactivity	B022 is an inhibitor of NF-ÎºB-inducing kinase (NIK) (Ki: 4.2 nM). B022 protects liver from oxidative stress, toxin-induced inflammation, and injury.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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