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Bragsin2

Bragsin2

Item no.	TMO-T14775-50mg
Manufacturer	TargetMol
CASRN	342795-08-8
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	COc1ccc2oc(cc(=O)c2c1[N+]([O-])=O)C(F)(F)F
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	289.16
Description	Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) is a hydration-resistant cell penetrant, selective and non-competitive inhibitor of Afr guanine nucleotide exchange factor BRAG2 that inhibits Arf GTPase activation, with an IC50 of 3 μM. Bragsin2 binds at the interface between the pleckstrin homology domain of BRAG2 and the lipid bilayer, leading BRAG2 unable to activate lipidated Arf GTPase.
Pathways	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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