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CCT251236

CCT251236

Item no.	TMO-T14905-1ml
Manufacturer	TargetMol
CASRN	1693731-40-6
Amount	1 mL
Quantity options	100 mg 100 mg 1 mL x 10 mM (in DMSO) 1 mL x 10 mM (in DMSO) 10 mg 10 mg 1 mg 1 mg 1 mL 200 mg 200 mg 25 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C32H32N4O5
Smiles	Cc1ccc(NC(=O)c2ccc3OCCOc3c2)cc1NC(=O)c1ccc2nc(OCCN3CCCC3)ccc2c1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	HSP
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	552, 62
Description	CCT251236 is a cell-based phenotypic high-throughput screening (HTS) chemical probe developed to screen for inhibitors of the HSF1 stress pathway.CCT251236 exhibits antimyeloma activity and inhibits HSF1.
Pathways	Cytoskeletal Signaling\|\|\|Metabolism
Bioactivity	CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen. It inhibits HSF1-mediated HSP72 induction (IC50: 19 nM).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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