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KIN1408

KIN1408

Item no.	TMO-T15662-500mg
Manufacturer	TargetMol
CASRN	1903800-11-2
Amount	500 mg
Quantity options	100 mg 10 mg 1 mg 200 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C25H19F2N3O3S
Smiles	COc1ccc2sc(NC(c3ccc(OC(F)F)cc3)c3ccc4cccnc4c3O)nc2c1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	KIN 1408
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Antiviral
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	479.5
Description	KIN1408 is an antiviral small molecule compound that is an agonist of the RIG-1-like receptor (RLR) pathway and is able to drive the activation of IRF3 (Interferon Regulatory Factor 3) to induce the expression of innate immunity genes (e.g., MDA5, RIG-1, Mx1, IRF7, and IFIT1), and to promote the nuclear translocation of IRF3 by targeting MAVS (Mitochondrial Antiviral Signaling Protein) or its upstream IRF3 nuclear translocation by targeting MAVS (mitochondrial antiviral signaling protein) or its upstream factors. KIN1400 is the parent, and KIN1409 is a derivative.
Pathways	Immunology/Inflammation
Bioactivity	KIN1408 is an antiviral small molecule compound. KIN1408 also is an agonist of the RLR pathway.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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