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Lofepramine

Lofepramine

Item no.	TMO-T15773-50mg
Manufacturer	TargetMol
CASRN	23047-25-8
Amount	50 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	C(CCN(CC(=O)C1=CC=C(Cl)C=C1)C)N2C=3C(CCC=4C2=CC=CC4)=CC=CC3
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Gamanil,Amplit,Leo 640,Lopramine
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Norepinephrine\|\|\|5-HT Receptor
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	418.96
Description	Lofepramine (Leo 640) is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors.
Pathways	GPCR/G Protein\|\|\|Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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