Ogerin

Item no.	TMO-T16378-200mg
Manufacturer	TargetMol
CASRN	1309198-71-7
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 1 mg 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C17H17N5O
Smiles	Nc1nc(NCc2ccccc2)nc(n1)-c1ccccc1CO
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	5-HT Receptor,5-HT Receptor,Adenosine Receptor,Adenosine Receptor,
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Adenosine Receptor\|\|\|5-HT Receptor
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	307.35
Description	Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83) that blocks recall in fear conditioning in mice. It exhibits inverse agonist and antagonist activity (Ki, 220 nM) at the A2A receptor and weak antagonist activity (Ki, 736 nM) at the 5-HT2B receptor.
Pathways	GPCR/G Protein\|\|\|Neuroscience
Bioactivity	Ogerin is a selective GPR68 positive allosteric modulator (pEC50: 6.83). Ogerin blocks recall in fear conditioning in mice. Ogerin displays inverse agonist and antagonist activity (Ki, 220 nM) at A2A receptor and weak antagonist activity (Ki, 736 nM) at 5

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