« Back
Home /
Pico145

Pico145

Item no.	TMO-T16532-200mg
Manufacturer	TargetMol
CASRN	1628287-16-0
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C23H20ClF3N4O5
Smiles	Cn1c2nc(Oc3cccc(OC(F)(F)F)c3)n(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	HC-608
Shipping Condition	Cool pack
Available
Manufacturer - Targets	TRP/TRPV Channel
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	524.88
Description	Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, specifically inhibiting ( )-englerin A-activated TRPC4/TRPC5 channels with IC50s of 0.349 and 1.3 nM in cells, while showing no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, or TRPM8.
Pathways	Membrane transporter/Ion channel
Bioactivity	Pico145 is a remarkable inhibitor of TRPC1/4/5 channels. Pico145 inhibits (âˆ’)-englerin A-activated TRPC4/TRPC5 channels (IC50s: 0.349 and 1.3 nM in cells) It also shows no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, TRPM8.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T16532-200mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 200 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question