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S 18986

S 18986

Item no.	TMO-T16816-2mg
Manufacturer	TargetMol
CASRN	175340-20-2
Amount	2 mg
Quantity options	10 mg 10 mg 1 mg 1 mg 25 mg 25 mg 2 mg 50 mg 50 mg 5 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C10H12N2O2S
Smiles	O=S1(=O)C=2C(N3[C@@](N1)(CCC3)[H])=CC=CC2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	iGluR\|\|\|GluR
Shipping Temperature	Cool pack
Storage Conditions	-20°C
Molecular Weight	224, 28
Description	S 18986 is a selective, orally active, brain-penetrant positive allosteric modulator of AMPA-type receptors that enhances cognition in rodents by inducing the release of noradrenaline and acetylcholine in the rat hippocampus, subsequently improving object-recognition memory.
Pathways	Neuroscience\|\|\|Membrane transporter/Ion channel
Bioactivity	S 18986 displays cognitive enhancing properties in rodents. S 18986 is a selective and brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances r

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