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SB-218078

SB-218078

Item no.	TMO-T16848-100mg
Manufacturer	TargetMol
CASRN	135897-06-2
Amount	100 mg
Quantity options	100 mg 10 mg 1 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	O=C1NC(=O)c2c1c1c3ccccc3n3C4CCC(O4)n4c5ccccc5c2c4c13
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	PKC,PKC,Chk
Shipping Condition	Cool pack
Available
Manufacturer - Targets	PKC\|\|\|Chk
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	393.39
Description	SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM). SB-218078 is a potent, ATP-competitive, and cell-permeable checkpoint kinase 1 inhibitor that inhibits Chk1 phosphorylation of cdc25C (IC50: 15 nM).
Pathways	Cytoskeletal Signaling\|\|\|Chromatin/Epigenetic\|\|\|Cell Cycle/Checkpoint

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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