TZ9

Item no.	TMO-T17187-1ml
Manufacturer	TargetMol
CASRN	1002789-86-7
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C17H14N6O4
Smiles	Nc1nc(COC(=O)c2ccc(cc2)[N+]([O-])=O)nc(Nc2ccccc2)n1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Apoptosis\|\|\|E1/E2/E3 Enzyme
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	366.33
Description	TZ9 is a selective and potent Rad6 inhibitor with anticancer and anti-tumor activity.TZ9 inhibits Rad6B-induced ubiquitination of histone H2A.TZ9 induces cell cycle arrest and apoptosis.
Pathways	Ubiquitination\|\|\|Apoptosis
Bioactivity	TZ9 is a novel inhibitor of the Rad6 ubiquitin-conjugating enzyme and it also inhibits MDA-MB-231 cell proliferation (IC50: ~6 uM).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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