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(S,R,S)-AHPC TFA

(S,R,S)-AHPC TFA

Item no.	TMO-T17927-50mg
Manufacturer	TargetMol
CASRN	1631137-51-3
Amount	50 mg
Quantity options	100 mg 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)N)=O)C[C@H](O)C3.O=C(O)C(F)(F)F
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	VH032-NH2 TFA,VHL ligand 1 TFA
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Ligand for E3 Ligase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	544.59
Description	(S, R, S)-AHPC TFA (VHL ligand 1 TFA) (VH032-NH2 TFA) is a VH032-based ligand designed for von Hippel-Lindau (VHL) protein recruitment. This compound can be linked to protein ligands (e.g., BCR-ABL1) using a linker to create PROTACs (e.g., GMB-475), which effectively induce the degradation of BCR-ABL1, demonstrated by an IC50 of 1.11 μM in Ba/F3 cells.
Pathways	PROTAC

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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