LOM612

Item no.	TMO-T19405-200mg
Manufacturer	TargetMol
CASRN	2173232-79-4
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C13H10N2O2S
Smiles	O=C1C=2SN=C(C2C(=O)C=3C=CC=CC13)N(C)C
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	LOM 612
Shipping Condition	Cool pack
Available
Manufacturer - Targets	FOXO3\|\|\|FOXO1
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	258.3
Description	LOM612 is a potent and specific FOXO relocator that induces nuclear translocation of the FOXO3a reporter protein as well as endogenous FOXO3a and FOXO1 in a dose-dependent manner in U2OS cells, down-regulates the expression of c-Myc and cyclin D1, and has anti-proliferative effects in human cancer cell lines.
Pathways	Apoptosis
Bioactivity	LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 Î¼M in U2fox RELOC cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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