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Sivelestat sodium

Sivelestat sodium

Item no.	TMO-T21414-500mg
Manufacturer	TargetMol
CASRN	150374-95-1
Amount	500 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 2 mg 500 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C20H21N2NaO7S
Smiles	O=C(CNC(C1=C(NS(=O)(C2=CC=C(C=C2)OC(C(C)(C)C)=O)=O)C=CC=C1)=O)[O-].[Na+]
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	ONO5046 sodium,EI 546 sodium,EI546 sodium,ONO 5046 sodium,LY-544349 sodium,LY544349 sodium
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Serine Protease\|\|\|SARS-CoV
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	456.45
Description	Sivelestat sodium (EI 546 sodium) is a highly efficient inhibitor of human neutrophil elastase, improving sepsis-induced myocardial dysfunction by activating the PI3K/AKT/mTOR signaling pathway. It can be used in acute lung injury/acute respiratory distress syndrome research.
Pathways	Proteases/Proteasome\|\|\|Microbiology/Virology
Bioactivity	Sivelestat, an inhibitor of human neutrophil elastase, is used in the treatment of acute respiratory failure. Preliminary studies show Sivelestat may improve neuropathic pain.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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