Comparison

SKLB-163 European Partner

Item no. TMO-T26193-200mg
Manufacturer TargetMol
CASRN 1255099-06-9
Amount 200 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Formula C18H16ClN3O2S2
Smiles S(CC(NCC1=CC=CC=C1)=O)C2=NC=3C(S2)=CC(NC(CCl)=O)=CC3
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias SKLB163
Shipping Condition Cool pack
Available
Manufacturer - Targets
MAPK|||Rho|||Caspase|||Akt|||JNK
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
405.92
Description
SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK.
Pathways
PI3K/Akt/mTOR signaling|||Cell Cycle/Checkpoint|||Apoptosis|||MAPK|||Proteases/Proteasome|||Cytoskeletal Signaling
Bioactivity
SKLB-163 is an anticancer agent that acts by downregulating RhoGDI, decreasing phosphorylated Akt and p44/42 MAPK, and activating JNK-1 signaling pathway and caspase-3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 200 mg
Available: In stock
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