EF24

Item no.	TMO-T27242-5mg
Manufacturer	TargetMol
CASRN	342808-40-6
Amount	5 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 g 1 mg 200 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C19H16ClF2NO
Smiles	Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	EF 24,EF-24,3,5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone
Shipping Condition	Cool pack
Available
Manufacturer - Targets	ERK\|\|\|MEK\|\|\|Caspase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	311.33
Description	EF24 (3, 5-Bis[(2-fluorophenyl)Methylene]-4-piperidinone) treatment increases the levels of activated caspase 3 and 9, and decreases the phosphorylated forms of MEK1 and ERK. EF24 shows potent anti-tumor activity in oral squamous cell carcinoma (OSCC) via deactivation of the MAPK/ERK signaling pathway.
Pathways	MAPK\|\|\|Apoptosis\|\|\|Proteases/Proteasome

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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