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Fascaplysin chloride

Fascaplysin chloride

Item no.	TMO-T27305-100mg
Manufacturer	TargetMol
CASRN	114719-57-2
Amount	100 mg
Quantity options	100 mg 1 mg 500 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C18H11ClN2O
Smiles	[Cl-].O=C1C2=C(C=CC=C2)[N+]2=C1C1=C(C=C2)C2=CC=CC=C2N1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	NSC 622398,NSC622398,NSC-622398,Fascaplysin
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	306.75
Description	Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 μM). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.
Pathways	Others
Bioactivity	Fascaplysin is a cyclin D kinase 4/ cyclin D1 inhibitor (IC50 = 0.35 Î¼M). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K/AKT/mTOR signaling cascade in human leukemia HL-60 cells.

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