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K-14585

K-14585

Item no.	TMO-T27708-500mg
Manufacturer	TargetMol
CASRN	880546-17-8
Amount	500 mg
Quantity options	100 mg 500 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C51H56Cl2N8O4
Smiles	C(C=1C=2C(N(CC3=C(Cl)C=CC=C3Cl)C1)=CC=C(NC(NCC(N[C@H](C(N[C@H](C(NC(C4=CC=CC=C4)C5=CC=CC=C5)=O)CC6=CC=CC=C6)=O)CCCCN)=O)=O)C2)N7CCCC7
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	915.95
Description	K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone increased IL-8.
Pathways	Others
Bioactivity	K-14585 is a proteinase-activated receptor 2 antagonist. K-14585 inhibited PAR(2)-mediated p65 NFkappaB phosphorylation and NFkappaB-DNA binding. K-14585 inhibited SLIGKV-stimulated IL-8 production, but given alone increased IL-8.

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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