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Ro 41-5253

Ro 41-5253

Item no.	TMO-T28589-500mg
Manufacturer	TargetMol
CASRN	144092-31-9
Amount	500 mg
Quantity options	100 mg 1 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C28H36O5S
Smiles	CCCCCCCOc1cc2c(cc1\C(C)=C\c1ccc(cc1)C(O)=O)C(C)(C)CCS2(=O)=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Ro-41-5253,Ro 415253
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Retinoid Receptor\|\|\|Apoptosis
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	484.65
Description	Ro 41-5253 is an orally active RARα antagonist, ligand, and partial agonist of peroxisome proliferator-activated receptor (PPAR)-γ. It exhibits antitumor activity, inhibits proliferation, and induces apoptosis in MCF-7 and ZR-75.1 estrogen receptor-positive breast cancer cells.
Pathways	Apoptosis\|\|\|Metabolism
Bioactivity	Ro 41-5253 is a selective antagonist of RARÎ±. Ro 41-5253 inhibits connexin 43 protein expression induced by retinoic acid in 10T1/2 cells.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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