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SKI2852

SKI2852

Item no.	TMO-T28796-100mg
Manufacturer	TargetMol
CASRN	1346554-47-9
Amount	100 mg
Quantity options	100 mg 10 mg 1 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C27H34FN5O4S
Smiles	N(C(=O)C1=NC(=NC=C1)N2[C@H](C)CN(CC2)C3=C(F)C=C(S(C)(=O)=O)C=C3)[C@@H]4[C@]5(CC6(O)C[C@@]4(CC(C5)C6)[H])[H]
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	SKI-2852
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Dehydrogenase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	543.65
Description	SKI2852 is an orally active, selective, and efficient 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor, improving metabolic syndrome in diabetic mouse models.
Pathways	Metabolism
Bioactivity	SKI2852 is a highly Potent, selective, and orally bioavailable inhibitor of 11Î²-Hydroxysteroid Dehydrogenase Type 1 (11Î²-HSD1). hHSD1 IC50 = 2.9nM; mHSD1 IC50 = 1.6nM.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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