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IWP-051

IWP-051

Item no.	TMO-T32242-100mg
Manufacturer	TargetMol
CASRN	1354041-91-0
Amount	100 mg
Quantity options	100 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	C(N1C(=CC(=N1)C=2NC(=O)C(F)=CN2)C=3C=CON3)C4=C(F)C=CC=C4
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	IWP051
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	355.3
Description	IWP-051 is a potent, orally active sGC stimulator (EC50 = 290nM). IWP-051 showed > 99% plasma protein binding, high metabolic stability, high permeability, and no efflux in a Caco-2 model of intestinal absorption. IWP-051 achieves good alignment of potency, stability, selectivity, and pharmacodynamic effects while maintaining favorable pharmacokinetic properties with once-daily dosing potential in humans.
Pathways	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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