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JH-IX-179

JH-IX-179

Item no.	TMO-T32288-500mg
Manufacturer	TargetMol
CASRN	T32288
Amount	500 mg
Quantity options	100 mg 500 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	O=C1C2=C(NC3=C2C=CC(C4=CNN=C4)=C3)C5=C1C=CC(C6=CN(CCCN(C)C)N=C6)=C5
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	JH-IX179,JH-IX 179
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	436.52
Description	JH-IX-179 is a novel type I ATP competitive and highly selective FLT3 inhibitor. JH-IX-179 is much more selective for FLT3 and FLT3 mutants than for Kronani. In addition, JH-IX-179 showed little human serum protein binding and effectively inhibited autophosphorylation of FLT3 and activity of downstream signaling molecules of FLT3-D835Y and FLT3-ITD.
Pathways	Others

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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