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Tyrphostin 8

Tyrphostin 8

Item no.	TMO-T34973-500mg
Manufacturer	TargetMol
CASRN	3785-90-8
Amount	500 mg
Quantity options	100 mg 10 mg 25 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C10H6N2O
Smiles	OC1=CC=C(C=C(C#N)C#N)C=C1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	4-Hydroxybenzylidenemalononitrile
Shipping Condition	Cool pack
Available
Manufacturer - Targets	EGFR\|\|\|GTPase\|\|\|Phosphatase
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	170.17
Description	Tyrphostin 8(4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances transferrin receptor-mediated transcytosis in Caco-2 cells, and increases the hypoglycemic effect of oral insulin-transferrin. hypoglycemic effect.
Pathways	JAK/STAT signaling\|\|\|GPCR/G Protein\|\|\|Metabolism\|\|\|Tyrosine Kinase/Adaptors\|\|\|Angiogenesis
Bioactivity	Tyrphostin 8 is a bioactive chemical.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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