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UNIL-088

UNIL-088

Item no.	TMO-T34999-500mg
Manufacturer	TargetMol
CASRN	473545-11-8
Amount	500 mg
Quantity options	100 mg 25 mg 500 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C73H128N13O22P
Smiles	[H][C@@]1([C@H](OC(=O)CN(C)C(=O)[C@H](COP(O)(O)=O)NC(=O)OC(C)OC(C)=O)[C@H](C)C\C=C\C)N(C)C(=O)C(C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)C(NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C(=O)[C@H](CC)NC1=O)C(C)C \|@@:39,107\|
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	UNIL 088
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Others
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	1570.87
Description	UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapidly hydrolysed under physiological conditions, and can retain a long shelf-life in aqueous media. UNIL-088 is more stable at pH 5 than at pH 7 with conversion rate constant of 3.2 x 10(-3) and 26.0 x 10(-3)days(-1), respectively.
Pathways	Others
Bioactivity	UNIL088 is a water-soluble prodrug of cyclosporine A (CsA) designed for topical ocular delivery. The pro-moiety is grafted via an ester function to CsA and the solubilizing group is a phosphate ion. UNIL-088 can be rapidly hydrolysed under physiological c

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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