SHP099

Item no.	TMO-T3564-200mg
Manufacturer	TargetMol
CASRN	1801747-42-1
Amount	200 mg
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Formula	C16H19Cl2N5
Smiles	CC1(N)CCN(CC1)c1cnc(c(N)n1)-c1cccc(Cl)c1Cl
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	SHP-099,SHP 099,SHP099 free base
Shipping Condition	Cool pack
Available
Manufacturer - Targets	Phosphatase\|\|\|PERK
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	352.26
Description	SHP099 (SHP099 free base) free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 μM and p-ERK modulation in cells IC50 = 0.250 μM). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
Pathways	Metabolism\|\|\|Apoptosis
Bioactivity	SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 Î¼M and p-ERK modulation in cells IC50 = 0.250 Î¼M). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

TMO-T3564-200mg-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 200 mg

available

Compare

Add to wishlist

Get an offer

Request delivery time

Ask a technical question