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SB 271046 hydrochloride

SB 271046 hydrochloride

Item no.	TMO-T4118-1ml
Manufacturer	TargetMol
CASRN	209481-24-3
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	Cl.C[C@@H](CN1CC(=O)NC(=O)C1)N1CC(=O)NC(=O)C1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	SB 271046A
Shipping Condition	Cool pack
Available
Manufacturer - Targets	5-HT Receptor
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	488.45
Description	SB 271046 hydrochloride (SB 271046A) is selective, orally active 5-HT6 antagonist (pKi values are 9.02-8.92, 6.35, 6.55, 6.27 at 5-HT6, 5-HT1A, 5-HT1D and D3, and 6.05, 5.95, 5.76, 5.73, 5.62, 5.55, 5.41, 5.39, 5.27 and < 4.99 at 5-HT1B, 5-HT1F, α1B, 5-HT2C, 5-HT2A, D2, 5-HT2B, 5-HT7, 5-HT4 and 5-HT1E respectively) and is > 200-fold selective over 55 other receptors, enzymes and ion channels. It increases extracellular aspartate and glutamate in the frontal cortex and exhibits anticonvulsant activity (EC50: 0.16 μM).
Pathways	GPCR/G Protein\|\|\|Neuroscience

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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