BPTU

Item no.	TMO-T4132-1ml
Manufacturer	TargetMol
CASRN	870544-59-5
Amount	1 mL
Quantity options	100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	CC(C)(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	BMS-646786
Shipping Condition	Cool pack
Available
Manufacturer - Targets	P2Y Receptor
Shipping Temperature	Cool pack
Storage Conditions	-20
Molecular Weight	445.43
Description	BPTU (BMS-646786) is an allosteric antagonist of P2Y1 (EC50 = 0.06-0.3 μM). Non-nucleotide ligand. Binds receptor outside of the helical bundle. Blocks inhibition of spontaneous contraction of rat and mouse colon induced by electrical field stimulation, nicotine and P2Y agonists. Antithrombotic; reduces platelet aggregation.
Pathways	GPCR/G Protein\|\|\|Neuroscience

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