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MS049 2HCl (1502816-23-0(free base))

MS049 2HCl (1502816-23-0(free base))

Item no.	TMO-T4393-1ml
Manufacturer	TargetMol
CASRN	T4393
Amount	1 mL
Quantity options	100 mg 10 mM x 1 mL (in DMSO) 10 mg 1 mL 200 mg 25 mg 2 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Smiles	Cl.Cl.CNCCN1CCC(CC1)OCc2ccccc2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	Histone Methyltransferase
Shipping condition	Cool pack
Available
Manufacturer - Targets	Histone Methyltransferase
Shipping Temperature	cool pack
Storage Conditions	-20°
Molecular Weight	321, 28
Description	MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 μM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested.
Pathways	Chromatin/Epigenetic

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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