Comparison

Go6976 European Partner

Item no. TMO-T6515-500mg
Manufacturer TargetMol
CASRN 136194-77-9
Amount 500 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 25 mg 500 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Formula C24H18N4O
Smiles Cn1c2ccccc2c2c3C(=O)NCc3c3c4ccccc4n(CCC#N)c3c12
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias Gö 6976
Shipping Condition Cool pack
Available
Manufacturer - Targets
PKC
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
378.43
Description
Go6976 is a small molecule inhibitor of protein kinase C (PKC). Go6976 has been widely used in biomedical research as a tool to study the role of PKC in various physiological and pathophysiological processes.
Pathways
Cytoskeletal Signaling|||Chromatin/Epigenetic
Bioactivity
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat brain), PKCα, and PKCβ1, respectively. Also a potent inhibitor of JAK2 and Flt3.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
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