Comparison

A-1155463 European Partner

Item no. TMO-T6748-1ml
Manufacturer TargetMol
CASRN 1235034-55-5
Amount 1 mL
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 1 mL 25 mg 2 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Smiles C(NC1=NC=2C(S1)=CC=CC2)(=O)C3=C4C(CCN(C4)C5=NC(C(O)=O)=C(CCCOC6=C(F)C=C(C#CCN(C)C)C=C6)S5)=CC=C3
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias A 1155463,A1155463
Shipping Condition Cool pack
Available
Manufacturer - Targets
Bcl-2 Family
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
669.79
Description
A-1155463, a highly potent and selective BCL-XL inhibitor, shows picomolar binding affinity to BCL-XL, and >1000-fold weaker binding to BCL-2 and related proteins BCL-W(Ki=19 nM) and MCL-1(Ki>440 nM).
Pathways
Apoptosis

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 1 mL
Available: In stock
available

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