Comparison

Avosentan European Partner

Item no. TMO-TQ0282-500mg
Manufacturer TargetMol
CASRN 290815-26-8
Amount 500 mg
Quantity options 100 mg 1 mL x 10 mM (in DMSO) 10 mg 1 mg 200 mg 25 mg 2 mg 500 mg 50 mg 5 mg
Category
Type Chemicals
Specific against other
Formula C23H21N5O5S
Smiles COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(nc1OC)-c1ccncc1
ECLASS 10.1 32160000
ECLASS 11.0 32160000
UNSPSC 12000000
Alias SPP-301,Ro 67-0565
Shipping Condition Cool pack
Available
Manufacturer - Targets
Endothelin Receptor
Shipping Temperature
Cool pack
Storage Conditions
-20
Molecular Weight
479.51
Description
Avosentan(Ro 67-0565; SPP-301) is a potent endothelin receptor (ETA) antagonist with strong inhibitory effects on endothelin-1-induced contraction and may have protective effects against chronic kidney disease. [2]
Pathways
GPCR/G Protein
Bioactivity
Avosentan (Ro 67-0565) is an effective and selective antagonist of the endothelin receptor (ETA receptor).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 500 mg
Available: In stock
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