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N1-Methylpseudouridine-5′-triphosphate (trisodium) solution (100mM)

N1-Methylpseudouridine-5′-triphosphate (trisodium) solution (100mM)

Item no.	HY-112582C-56410ug
Manufacturer	MedChem Express
Amount	56.41 mg (100 mM * 1 mL in water)
Quantity options	11.28 mg (100 mM * 200 uL in water) 11282 ug (100 mMx200 uL in water) 1 ea 28.20 mg (100 mM * 500 uL in water) 28205 ug (100 mMx500 uL in water) 28210 ug (100 mM x 500 ul in water) 5.64 mg (100 mM * 100 uL in water) 56.41 mg (100 mM * 1 mL in water) 56411 ug (100 mMx1 mL in water) 5641 ug (100 mMx100 uL in water)
Category	Reagents & Chemicals Other Chemicals
Type	Chemicals
Specific against	other
Purity	99.0
Formula	C10H14N2Na3O15P3
Dry ice	Yes
Citations	[1]Andries O, Mc Cafferty S, De Smedt SC, Weiss R, Sanders NN, Kitada T. N(1)-methylpseudouridine-incorporated mRNA outperforms pseudouridine-incorporated mRNA by providing enhanced protein expression and reduced immunogenicity in mammalian cell lines and mice. J Control Release. 2015;217:337-344.
Smiles	O[C@H]1[C@@H](O)[C@H](C(C(N2)=O)=CN(C)C2=O)O[C@@H]1COP(OP(OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	1-Methylpseudouridine-5′-triphosphate (trisodium) solution (100mM)
Shipping condition	Dry ice
Available
Manufacturer - Type	Biochemical Assay Reagents
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
Shipping Temperature	Dry Ice
Storage Conditions	-80°C
Molecular Weight	564.11
Product Description	N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100mM) is a nucleobase-modified nucleotide, used for synthesizing mRNA with reduced immunogenicity and improved stability[1].
Manufacturer - Research Area	Others
Solubility	H2O : ≥ 125 mg/mL
Manufacturer - Pathway	Cell Cycle/DNA Damage
Clinical information	No Development Reported

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HY-112582C-56410ug-safety-datasheet.pdf