BT-2

Item no.	DCC-DC55038-1g
Manufacturer	DCChemicals
CASRN	34576-94-8
Amount	1 g
Quantity options	100 mg 1 g 250 mg
Category	Reagents & Chemicals Molecules
Type	Chemicals
Applications	BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC)[1]. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM[2].
Specific against	other
Smiles	ClC1=CC2=C(C=C1)C(Cl)=C(C(O)=O)S2
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Manufacturer - Applications	BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC)[1]. BT2 (compound 4) is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM[2].
Molecular Weight	247, 09786

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

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