« Back
Home /
Lu AF27139

Lu AF27139

Item no.	DCC-DC60155-250mg
Manufacturer	DCChemicals
CASRN	2097117-06-9
Amount	250 mg
Quantity options	100 mg 1 g 250 mg
Category	In Vivo Reagents & Chemicals Molecules
Type	Chemicals
Applications	IV
Specific against	other
Smiles	ClC1=CC=C([C@H](N2CCOCC2)CN([H])C(C3=C(C(F)(F)F)N=C(C4=NC=CC=N4)S3)=O)C=C1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Manufacturer - Applications	Lu AF27139 is a novel rodent-active and CNS-penetrant P2X7 receptor antagonist. Lu AF27139 is highly selective and potent against rat, mouse, and human forms of the receptors. The rat pharmacokinetic profile is favorable with high oral bioavailability, modest clearance (0.79 L/(h kg)), and good CNS permeability. Importantly, Lu AF27139 was without effect in standard in vitro and in vivo toxicity studies. Lu AF27139 is a valuable tool for probing the role of the P2X7 receptor in rodent models of CNS diseases.
Molecular Weight	497, 9212

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 250 mg

available

Delivery expected until 11/13/2025

Express Delivery: Save 2 days

Compare

Add to wishlist

Get an offer