AZ194

Item no.	DCC-DC60184-100mg
Manufacturer	DCChemicals
CASRN	2241651-99-8
Amount	100 mg
Quantity options	100 mg 1 g 250 mg
Category	Reagents & Chemicals Molecules
Type	Chemicals
Applications	HUN51998, also known as CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor. HUN51998 was first reported in patent WO 2018144900, which functioned as a antagonist of small ubiquitin like modifier (SUMO) related modification (SUMOylation) of collapsin response mediator protein 2 (CRMP2) with potential application for the treatment of voltage gated sodium channel 1.7 (Nav1.7) related, anosmia, migraine event, and/or pain (e.g., neuropathic pain).
Specific against	other
Smiles	O=C(N1CCC(C2=NC3=CC=CC=C3N2CC4=CC=CC(F)=C4)CC1)C5=CC=C(OCC6=CC=CC(F)=C6)C(OC)=C5
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Available
Manufacturer - Applications	AZ-194 is a first-in-class, orally active inhibitor of CRMP2-Ubc9 interaction and inhibitor of NaV1.7 (IC50=1.2 μM). AZ194 blocks SUMOylation of CRMP2 to selectively reduce the amount of surface-expressed NaV1.7. Antinociceptive effects[1].
Molecular Weight	567, 64

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 mg

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