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9-Phenanthrol

9-Phenanthrol

Item no.	HY-108457-100mg
Manufacturer	MedChem Express
CASRN	484-17-3
Amount	100 mg
Quantity options	100 mg 10 mM/1 mL 1 ea 1 g 250 mg 25 mg 500 mg 50 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.61
Citations	[1]Wang J, et, al. 9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury. PLoS One. 2013 Jul 25;8(7):e70587. \|[2]Guinamard R, et al. The TRPM4 channel inhibitor 9-phenanthrol. Br J Pharmacol. 2014 Apr;171(7):1600-13.
Smiles	OC1=CC2=CC=CC=C2C3=CC=CC=C13
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Alias	9-Hydroxyphenanthrene,NSC 50554
Shipping Condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	TRP Channel
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	194.23
Product Description	9-Phenanthrol (9-Hydroxyphenanthrene) is a selective TRPM4 inhibitor with an IC50 of 17 μM. 9-Phenanthrol has no inhibitory activity on TRPM5, TRPC6, and CFTR. 9-Phenanthrol can be used for the research of ischemia-reperfusion injury[1][2].
Manufacturer - Research Area	Cardiovascular Disease
Solubility	DMSO: 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Membrane Transporter/Ion Channel; Neuronal Signaling
Isoform	TRPM
Clinical information	No Development Reported

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HY-108457-100mg-safety-datasheet.pdf