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Hsp90-Cdc37-IN-1

Hsp90-Cdc37-IN-1

Item no.	HY-111414-100mg
Manufacturer	MedChem Express
CASRN	2227303-22-0
Amount	100 mg
Quantity options	100 mg 10 mg 1 ea 25 mg 50 mg 5 mg
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	99.66
Citations	[1]Jin L, et al. Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. Bioorg Med Chem. 2018 May 1;26(8):1759-1775.
Smiles	C[C@@]1(C(OCC)=O)C[C@]2([H])[C@](CC[C@]([C@@]3(C)[C@@]4([H])[C@]5(C)[C@@](C(C)(C)[C@@H](OC(CCC(NC6=NC7=C(C=C(F)C=C7)S6)=O)=O)CC5)([H])CC3)(C)C2=CC4=O)(C)CC1
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping Condition	Cool pack
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Cancer-programmed cell death
Manufacturer - Targets	HSP
Shipping Temperature	Blue Ice
Storage Conditions	-20°C, 3 years (Powder)
Molecular Weight	748.99
Product Description	Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor that inhibit cell migration and reverse agent resistance, with an IC50 of 140 nM.
Manufacturer - Research Area	Cancer
Solubility	DMSO: 2.86 mg/mL (ultrasonic; warming; heat to 60°C)
Manufacturer - Pathway	Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Clinical information	No Development Reported

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HY-111414-100mg-safety-datasheet.pdf