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(Rac)-SAR131675

(Rac)-SAR131675

Item no.	HY-123050-100mg
Manufacturer	MedChem Express
CASRN	1092539-44-0
Amount	100 mg
Quantity options	100 mg 1 ea
Category	Reagents & Chemicals Biochemicals
Type	Chemicals
Specific against	other
Purity	98.0
Citations	[1]Mitroshina EV, et al. Neuroprotective Effect of Kinase Inhibition in Ischemic Factor Modeling In Vitro. Int J Mol Sci. 2021;22(4):1885. [2]Alam A, et al. SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. Mol Cancer Ther. 2012 Aug;11(8):1637-49.
Smiles	O=C(C1=C(N)N(CC)C2=C(C=CC(C#CC(C)(O)COC)=N2)C1=O)NC
ECLASS 10.1	32160000
ECLASS 11.0	32160000
UNSPSC	12000000
Shipping condition	Room temperature
Available
Manufacturer - Type	Reference compound
Manufacturer - Applications	Neuroscience-Neuromodulation
Manufacturer - Targets	VEGFR
Shipping Temperature	Room Temperature
Storage Conditions	-20°C, 3 years; 4°C, 2 years (Powder)
Molecular Weight	358.39
Product Description	(Rac)-SAR131675 is the racemate of SAR131675. SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM[1][2].
Manufacturer - Research Area	Neurological Disease
Solubility	10 mM in DMSO
Manufacturer - Pathway	Protein Tyrosine Kinase/RTK
Isoform	VEGFR3/Flt-4
Clinical information	No Development Reported

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All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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